Had Trustport some time ago on my winXP. Contained 5 virus programs inside.. Everyone tells me that's not possible @ that time.
Worked like a charm, but needed lots of memory.
Think now Kaspersky favors my wishes. But this one doesn't like other (anti) virus programs side-by-side. Thats a shame, but the choise is made and Kaspersky went out of the door.
Am now enforced with EsetNot32.

Always sworn by NOD32.

Kaspersky Internet Security 2018 with trial reseter

Comodo Internet Security 10

I have been using Kaspersky for 3 years and I'm happy with it!

There are some accusations towards Kaspersky.

I'm using ESET Endpoint at home and at work. For years it was always perfectly fine experience.

I m currently using Bit-Defender, pretty satisfied with it

My best antivirus: Linux acting as a firewall and 2 Windows virtual machines: one that donesn't have network access, and the other that I reset regularly. That way I also avoid unwanted software updates and and antipiracy snooping (like Adobe does, for example).

For tasks that really need a native Windows system (outside a virtual machine), I dual boot to a Windows system, that has no network connexion either.

the best should be a combination of a good av software and a up to date windows version. i use eset and regulary update windows. for business including office 365 i would recommend f-secure inclusive anti-ransomware plugin

Best antivirus? MacOS