A MAN has died after a fire broke out on the 50th floor of Trump Tower, the Manhattan headquarters of US President Donald Trump.

The blaze erupted in a residential apartment at the building, located on Fifth Avenue and 57th Street in New York City.

The male occupant of the apartment that was on fire died from his injuries after being taken to St. Luke’s Hospital in a critical condition.

In a media conference, FDNY Commissioner Daniel Nigro said “the apartment was virtually, entirely on fire” when they arrived.

Melania Trump and the couple’s son, Barron Trump, are both in Washington, D.C., according to the first lady’s spokeswoman, Stephanie Grisham.

The US President is also at the White House.

President Trump tweeted at 6.43pm local time that the fire had been extinguished.

Mr Trump’s son Eric also took to Twitter to thank the emergency services.