Jhye Richardson faces a nervous wait to determine the extent of a shoulder injury after it was confirmed the young paceman will depart Australia’s one-day series against Pakistan in the UAE.

Australia are hopeful Richardson will be fit to take part in the upcoming World Cup after he dislocated his right shoulder while fielding on the boundary in the second ODI in Sharjah on Sunday.

The 22-year-old immediately signalled for help after landing awkwardly and medical staff had to pop his shoulder back into place.

Richardson will fly home to Perth on Monday and will undergo scans to assess the damage. It's believed to be his first serious injury to his bowling shoulder.

He won't be replaced in Australia’s ODI squad.

"It's horrible to see," said Usman Khawaja, whose 209-run opening stand with Aaron Finch (153) helped Australia to an eight-wicket win. "It makes your stomach sink.

"You feel for him. He put his body on the line, trying to save a boundary.

"He was bowling beautifully. But he's a good kid, I'm sure he's going to come back much stronger whenever he does. Hopefully - fingers crossed - it's all good.

"It (Richardson's shoulder) went back in pretty easily, so that's always a good sign."

Richardson's exit from the UAE adds some complication to Australia's fast-bowling plans for not only the World Cup, but also the ensuing Ashes.

Neither Mitchell Starc (pectoral injury) and Josh Hazlewood (back) were risked for the back-to-back series against India and Pakistan, while Pat Cummins has sat out the opening two games of the ongoing tour in the UAE.

Richardson has had a breakthrough summer at international level, making his Test debut in January while pushing himself towards a World Cup berth with a series of impressive ODI bowling performances.

Teammate Nathan Lyon said he remained in good spirits despite the blow.

"He's obviously pretty shattered but he's trying to stay upbeat," said Lyon.

"It's very disappointing, especially off the back of the summer that Jhye's had. He's had a really good Shield season for WA then a pretty special Test series against Sri Lanka.

"The way he's been performing has been pretty impressive. Fingers crossed he can be fit for the World Cup and be in the selection (mix) there."

To further underline his credentials, Richardson had earlier in the match made two key inroads with the new ball on a lifeless surface and had 2-16 after five overs before his injury.

The right-armer is Australia’s leading wicket taker in ODI cricket this year with 17 wickets at 21.23 and has impressed teammates with his eager-to-learn attitude.

“He's someone who is always asking questions, always learning," captain Finch said ahead of the series. "Especially for a young kid - not all young kids are willing to learn as quickly as he is."

The injury could pave the way for Cummins to return for the third ODI in Abu Dhabi, while fellow quicks Kane Richardson and Jason Behrendorff will also come into contention.